Stereotactic radiosurgery in alveolar soft part sarcoma brain metastases: Case series and literature review

Alveolar soft part sarcoma (ASPS) are rare tumors, representing <1% of all soft tissue sarcomas [1]. It tends to occur with a female predisposition below the age of 20 and with a male predisposition thereafter [2,3]. ASPS metastasize frequently, but despite this the clinical course is usually indolent [3,4]. ASPS may have the highest incidence of brain metastasis amongst all sarcomas [5]. Brain metastases occur most often as part of a disseminated disease, resulting in a poor prognosis for these patients [3,5,6].