Individual differences in visual evoked potential latency are associated with variance in brain tissue volume in people with multiple sclerosis: An analysis of brain function-structure correlates

Visual evoked potentials (VEPs) are a useful clinical tool for evaluating pathophysiology of the visual system in people with multiple sclerosis (PwMS) (Backner et al., 2019; Barton et al., 2019; Chirapapaisan et al., 2015). VEPs are obtained by signal averaging ongoing electroencephalogram (EEG) data that has been time-locked to the onset of stimuli that are repeatedly presented to the patient. The signal averaged VEP is comprised of a series of positive and negative deflections in the waveform that constitute distinct peaks in amplitude, which are each related to different stages of information processing along the visual pathway.